Amethopterin Hydrate
Update:2014-11-25 0:59:40
| Item: | Amethopterin Hydrate | ||
| Synonym: | MTX ; 4-Amino-10-methylfolic acid; Methylaminopterin; (+)-Amethopterin hydrate | ||
| CAS No.: | 59-05-2 | Special Grade: | Biotech Grade |
| Formula: | C20H22N8O5 | M.W.: | 454.44 |
Order
| Product No. | Size | Price | Brand |
| A6770-10mg | 10mg | 160 | GBCBIO |
| A6770-50mg | 50mg | 450 | GBCBIO |
| A6770-1g | 1g | 7855 | Sigma |
Introduction
| Purity (HPLC)(%)..............................≥98.5 Water (Karl Fisher) (%).........................≤12 |
Folic acid antagonist. Amethopterin is actively transported into cells by the folate transporter. In the cell, it is converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase, that, in turn, binds to dihydrofolate red |
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